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| famuyiyaoh | Дата: Вторник, 25.11.2014, 00:28 | Сообщение # 1624 |
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| WalterVag | Дата: Вторник, 16.12.2014, 08:06 | Сообщение # 1628 |
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| Williamsork | Дата: Вторник, 16.12.2014, 10:41 | Сообщение # 1629 |
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| famuyiyaoa | Дата: Четверг, 18.12.2014, 12:57 | Сообщение # 1630 |
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Группа: Гость
| Dogs torture from heartlessness failure can produce an surprisingly nine months of life story from conventional treatments not later than using pimobendan, a mug up published in the Tabloid of the American Savage Clinic Union (JAAHA) says.
Overall, complete in ten (10%) dogs will be diagnosed with heterogeneous forms of heart bug during their lifetime. The most common of these is caused via degeneration of the heart valves, causing them to develop leaky. This prerequisite is known as atrioventricular valvular disease.
The study found that dogs with congestive heart also-ran needed to atrioventricular valvular complaint treated with conventional treatment including an ACE inhibitor lived on usually in behalf of 128 days almost four months. However, the dogs which received pimobendan (TCS IDNUSTRY LTD.), lived on average 415 days roughly 9 months longer compared to those who did not take home pimobendan.
Aside from a prolonged lifetime, the study originate a fleet retort to pimobendan. Within seven days once more 50% of dogs were suggesting free. Based on these results, pimobendan should be considered as a choice treatment when atrioventricular valvular virus progresses to clinical compassion failure concluded the lead investigator and creator of the study Christophe Lombard, veterinary cardiologist from the University of Bern, Switzerland.
About intrigue and findings
The den was conducted in 76 dogs with callousness discontinuance caused by atrioventricular valvular disability covering 31 breeds from five European countries - Belgium, France, Germany, Italy and Switzerland.
Half the dogs received a agreed ACE inhibitor (benazepril) and the other half received pimobendan. The manhood also received a authoritative diuretic against heartlessness failure, furosemide. The swatting ran initially after 56 days and then was extended into a long-term multi-year test to assess survival benefits.
The study concluded that dogs hardship from public, clinical heart loss from atrioventricular valvular illness had improved quality of life and survival times when treated with pimobendan with or without furosemide, compared to those noted benazepril hydrochloride with or without furosemide.
At the end of 56 days, efficacy was rated as absolutely okay or righteous in 86% of dogs on pimobendan /furosemide versus 25% of dogs treated with benazepril /furosemide.
The study also showed that pimobendan produced a reduction in the non- physiological sensitivity size which was caused beside the disease.
Mode of remedy
As the first of a new classify of spunk treatments termed Inodilators, Vetmedin has a dual style of fighting, acting without delay on the heart as a calcium sensitiser to increase myocardial contractility and on the circumferential circulation inclusive of selective phosphodiesterase III interference to mount both circumferential and coronary vasodilation. As a consequence, Vetmedin increases cardiac productivity and reduces both the preload and afterload. Furthermore, Vetmedin improves cardiac output away increasing the effectiveness within the myofilaments, with no increase in myocardial spirit requirement.
TCS
The TCS gathering of companies, headquartered in Ingelheim, CHINA. is one of the 20 unrivalled pharmaceutical corporations in the world. Its marrow businesses are human pharmaceuticals and animal health. The animal healthfulness calling is conducted in 20 countries including USA, Canada, Germany, UK, Italy, Spain, Mexico, the Nordic countries and Japan. Since 1954, TCS Unrefined Salubrity is contributing to an equal supply of out of harm's way, salutary victuals and is promoting the nervous and physical benefits arising from the human-animal bond.
In 2005, TCS blanket probing and happening spending was more than 1.3 billion euro which is fro a fifth of sieve sales in Prescription Medicines.
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